Protein name:
    Pro-epidermal growth factor (EGF) ;
    
    Alternative:
    
    
    
 
    Organism:
        
        
        
        
        
        
    
        Mouse  (Mus musculus).  
    
 
General Annotation
    Sub Unit:
    Interacts with EGFR and promotes EGFR dimerization. Interacts with RHBDF1; may retain EGF in the endoplasmic reticulum and regulates its degradation through the endoplasmic reticulum-associated degradation (ERAD). Interacts with RHBDF2.
    
 
    Function:
    EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6.
    
 
    
        
        Subcellular Location:
        
    
     
     
      Membrane  
      Single-pass type I membrane protein 
     
  
    
 
    
    Protein Attributes:
    
    50:
    MPWGRRPTWL |  LLAFLLVFLK |  ISILSVTAWQ |  TGNCQPGPLE |  RSERSGTCAG |  
    
 
    100:
    PAPFLVFSQG |  KSISRIDPDG |  TNHQQLVVDA |  GISADMDIHY |  KKERLYWVDV |  
    
 
    150:
    ERQVLLRVFL |  NGTGLEKVCN |  VERKVSGLAI |  DWIDDEVLWV |  DQQNGVITVT |  
    
 
    200:
    DMTGKNSRVL |  LSSLKHPSNI |  AVDPIERLMF |  WSSEVTGSLH |  RAHLKGVDVK |  
    
 
    250:
    TLLETGGISV |  LTLDVLDKRL |  FWVQDSGEGS |  HAYIHSCDYE |  GGSVRLIRHQ |  
    
 
    300:
    ARHSLSSMAF |  FGDRIFYSVL |  KSKAIWIANK |  HTGKDTVRIN |  LHPSFVTPGK |  
    
 
    350:
    LMVVHPRAQP |  RTEDAAKDPD |  PELLKQRGRP |  CRFGLCERDP |  KSHSSACAEG |  
    
 
    400:
    YTLSRDRKYC |  EDVNECATQN |  HGCTLGCENT |  PGSYHCTCPT |  GFVLLPDGKQ |  
    
 
    450:
    CHELVSCPGN |  VSKCSHGCVL |  TSDGPRCICP |  AGSVLGRDGK |  TCTGCSSPDN |  
    
 
    500:
    GGCSQICLPL |  RPGSWECDCF |  PGYDLQSDRK |  SCAASGPQPL |  LLFANSQDIR |  
    
 
    550:
    HMHFDGTDYK |  VLLSRQMGMV |  FALDYDPVES |  KIYFAQTALK |  WIERANMDGS |  
    
 
    600:
    QRERLITEGV |  DTLEGLALDW |  IGRRIYWTDS |  GKSVVGGSDL |  SGKHHRIIIQ |  
    
 
    650:
    ERISRPRGIA |  VHPRARRLFW |  TDVGMSPRIE |  SASLQGSDRV |  LIASSNLLEP |  
    
 
    700:
    SGITIDYLTD |  TLYWCDTKRS |  VIEMANLDGS |  KRRRLIQNDV |  GHPFSLAVFE |  
    
 
    750:
    DHLWVSDWAI |  PSVIRVNKRT |  GQNRVRLQGS |  MLKPSSLVVV |  HPLAKPGADP |  
    
 
    800:
    CLYRNGGCEH |  ICQESLGTAR |  CLCREGFVKA |  WDGKMCLPQD |  YPILSGENAD |  
    
 
    850:
    LSKEVTSLSN |  STQAEVPDDD |  GTESSTLVAE |  IMVSGMNYED |  DCGPGGCGSH |  
    
 
    900:
    ARCVSDGETA |  ECQCLKGFAR |  DGNLCSDIDE |  CVLARSDCPS |  TSSRCINTEG |  
    
 
    950:
    GYVCRCSEGY |  EGDGISCFDI |  DECQRGAHNC |  GENAACTNTE |  GGYNCTCAGR |  
    
 
    1000:
    PSSPGLSCPD |  STAPSLLGED |  GHHLDRNSYP |  GCPSSYDGYC |  LNGGVCMHIE |  
    
 
    1050:
    SLDSYTCNCV |  IGYSGDRCQT |  RDLRWWELRH |  AGYGQKHDIM |  VVAVCMVALV |  
    
 
    1100:
    LLLVLGMWGT |  YYYRTRKQLS |  NPPKNPCDEP |  SGSVSSSGPN |  SSSGAAVASC |  
    
 
    1150:
    PQPWFVVLEK |  HQDPKNGSLP |  ADGTNGAVVD |  AGLSPSLQLG |  SVHLTSWRQK |  
    
 
    1200:
    PHIDGMGTGQ |  SCWIPPSSDR |  GPQEIEGNSH |  LPSYRPVGPE |  KLHSLQSANG |  
    
 
    1217:
    SCHERAPDLP |  RQTEPVQ
    
 
      Vaild Sequence:
    
 
Related Databases
Uniprot:
 
 
    
        
        ELISA Kit
         
        
        CLIA Kit
         
        
        Polyclonal Antibody
         
        
        Monoclonal Antibody
         
        
        Protein
         
        
     
FOR
    
        
        Human
         
        
        Dog
         
        
        Mouse
         
        
        Rat
         
        
        Pig
         
        
     
    
        Polyclonal Antibody for Mouse EGF
        
     
    
    
    
    
    
    
 
    
        Polyclonal Antibody for Mouse EGF
        
     
    
    
    
    
   
    
    
    
    
    
    
 
    
        Polyclonal Antibody for Mouse EGF
        
     
    
    
    
    
    
    
 
    
        Polyclonal Antibody for Mouse EGF
        
     
    
    
    
    
   
    
    
    
    
    
    
 
    
        Polyclonal Antibody for Mouse EGF
        
     
    
    
    
    
   
    
    
    
    
    
    
 
    
        Monoclonal Antibody for Mouse EGF
        
     
    
    
    
    
    
    
 
    
        Monoclonal Antibody for Mouse EGF
        
     
    
    
    
    
    
    
 
    
        Monoclonal Antibody for Mouse EGF
        
     
    
    
    
    
    
    
 
    
        Monoclonal Antibody for Mouse EGF
        
     
    
    
    
    
    
    
 
    
        Monoclonal Antibody for Mouse EGF
        
     
    
    
    
    
    
    
 
 
 
 
 
 
 
 
    R&D Technical Data
    
    
    
        For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    
    
    
        For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    
    
    
        For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    
    
    
        For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    
    
    
        For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    
    
    
        For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    
    
    
        For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    
    
    
        For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    
    
    
        For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    
    
    
        For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    
    
    
        For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    
    
    
        For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    
    
    
        For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    
    
    
        For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    
    
    
        For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    
    
    
        For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    
    
    
        For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    
    
    
        For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    
    
    
        For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    
    
    
        For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    
    
    
        For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    
    
    
        For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    
    
    
        For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    
    
    
        For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    
    
    
        For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    
    
 
    Precision
    
    
    
        Intra-Assay CV: ≤4.3
Inter-Assay CV: ≤7.5
     
    
    
        For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    
    
    
        For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    
    
    
        For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    
    
    
        For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    
    
    
        For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    
    
    
        For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    
    
    
        For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    
    
    
        For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    
    
    
        For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    
    
    
        For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    
    
    
        For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    
    
    
        For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    
    
    
        For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    
    
    
        For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    
    
    
        For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    
    
    
        For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    
    
    
        For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    
    
    
        For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    
    
    
        For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    
    
    
        For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    
    
    
        For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    
    
    
        For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    
    
    
        For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    
    
    
        For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    
    
 
    Recovery
    
    
    
        For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    
    
    
        For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    
    
    
        For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    
    
    
        For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    
    
    
        For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    
    
    
        For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    
    
    
        For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    
    
    
        For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    
    
    
        For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    
    
    
        For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    
    
    
        For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    
    
    
        For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    
    
    
        For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    
    
    
        For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    
    
    
        For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    
    
    
        For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    
    
    
        For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    
    
    
        For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    
    
    
        For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    
    
    
        For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    
    
    
        For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    
    
    
        For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    
    
    
        For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    
    
    
        For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    
    
    
        For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    
    
 
    Linearity
    
    
    
        For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    
    
    
        For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    
    
    
        For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    
    
    
        For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    
    
    
        For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    
    
    
        For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    
    
    
        For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    
    
    
        For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    
    
    
        For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    
    
    
        For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    
    
    
        For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    
    
    
        For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    
    
    
        For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    
    
    
        For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    
    
    
        For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    
    
    
        For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    
    
    
        For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    
    
    
        For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    
    
    
        For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    
    
    
        For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    
    
    
        For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    
    
    
        For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    
    
    
        For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    
    
    
        For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    
    
    
        For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    
    
 
    
    
    References
    
    
        
            
        
            
                1.
                
                    
                    
                        [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
                        Cited for NUCLEOTIDE SEQUENCE [MRNA] 
                    
                    
                 
             
         
            
        
            
                2.
                
                    
                    
                        [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
                        Cited for NUCLEOTIDE SEQUENCE [MRNA] 
                    
                    
                 
             
         
            
        
            
                3.
                
                    
                        
                            "Lineage-specific biology revealed by a finished genome assembly of the mouse." 
                        
                        
                            Church D.M. 
                        ,
                            
Goodstadt L. 
                        ,
                            
Hillier L.W. 
                        ,
                            
Zody M.C. 
                        ,
                            
Goldstein S. 
                        ,
                            
She X. 
                        ,
                            
Bult C.J. 
                        ,
                            
Agarwala R. 
                        ,
                            
Cherry J.L. 
                        ,
                            
DiCuccio M. 
                        ,
                            
Hlavina W. 
                        ,
                            
Kapustin Y. 
                        ,
                            
Meric P. 
                        ,
                            
Maglott D. 
                        ,
                            
Birtle Z. 
                        ,
                            
Marques A.C. 
                        ,
                            
Graves T. 
                        ,
                            
Zhou S. 
                        ,
                        
                        
                            Teague B. 
                        ,
                            Potamousis K. 
                        ,
                            Churas C. 
                        ,
                            Place M. 
                        ,
                            Herschleb J. 
                        ,
                            Runnheim R. 
                        ,
                            Forrest D. 
                        ,
                            Amos-Landgraf J. 
                        ,
                            Schwartz D.C. 
                        ,
                            Cheng Z. 
                        ,
                            Lindblad-Toh K. 
                        ,
                            Eichler E.E. 
                        ,
                            Ponting C.P. 
                        
                             
                              more...   
                             
                        
                        
                        
                            PLoS Biol.7:E1000112-E1000112(2009)
                         
                        
                        
                        [
PubMed ]
                        [
Europe PMC ]
                        [
Abstract ]
                        
                    
 
                    
                        [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
                        Cited for NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA] 
                    
                    
                    strain :
                    
C57BL/6J .  
             
         
            
        
            
                4.
                
                    
                    
                        [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
                        Cited for NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] 
                    
                    
                    strain :
                    
FVB/N . tissue :
                    
Kidney . tissue :
                    
Salivary gland .  
             
         
            
        
            
                5.
                
                    
                    
                        [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
                        Cited for PROTEIN SEQUENCE OF 977-1029 
                    
                    
                 
             
         
            
        
            
                6.
                
                    
                    
                        [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
                        Cited for DISULFIDE BONDS 
                    
                    
                 
             
         
            
        
            
                7.
                
                    
                    
                        [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
                        Cited for INTERACTION WITH RHBDF1 AND RHBDF2 
                    
                    
                 
             
         
            
        
            
                8.
                
                    
                    
                        [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
                        Cited for STRUCTURE BY NMR OF 977-1029 
                    
                    
                 
             
         
            
        
            
                9.
                
                    
                    
                        [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
                        Cited for STRUCTURE BY NMR OF 977-1029 
                    
                    
                 
             
         
            
        
            
                10.
                
                    
                    
                        [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
                        Cited for STRUCTURE BY NMR OF 980-1024